Inflammation in the body is a mechanism thought to be at the center of the majority of chronic diseases. Certain inflammatory factors in our blood, like C-reactive protein (CRP), have been identified as predictors of cardiovascular disease, cancer, and other chronic diseases. Fortunately, the foods and nutrients you choose to eat can have an impact on inflammation including certain fats, antioxidants, dietary fiber, arginine, and magnesium. For example, linoleic acid, an omega-6 fatty acid found in peanuts, has been shown to reduce inflammation. In fact, the 2009 American Heart Association Advisory Panel recommended that Americans include omega-6 in their diets, citing its benefits in reducing inflammation.
Foods with low glycemic loads have been shown to decrease inflammation as well. Fortunately, peanuts are a low-glycemic index food and are full of anti-inflammatory ingredients. A relationship has also been observed between frequent peanut consumption and reduced inflammatory factors. A 2016 study published in the American Journal of Clinical Nutrition examined over 5,000 participants. Results showed that peanut intake was associated with lower markers of inflammation in the blood. This may be why peanuts are associated with a reduced risk of cardiovascular disease and diabetes.
Since many Americans don’t consume levels of magnesium that match the Recommended Dietary Allowance (RDA), a small number of peanuts daily is a great way to boost intake. A study at Purdue University showed that eating peanuts every day increases blood magnesium too!
For those who don’t get enough magnesium, one study showed that levels of inflammation-causing CRP was more likely to be elevated. Another study looking at more than 11,000 women from the Women’s Health Study showed that low magnesium intake was associated with an increased risk of inflammation.
Innes JK, Calder PC. Omega-6 fatty acids and inflammation. Prostaglandins Leukot Essent Fatty Acids. 2018 May;132:41-48. doi: 10.1016/j.plefa.2018.03.004. Epub 2018 Mar 22. Review. PubMed PMID: 29610056.
Yu Z, Malik VS, Keum N, Hu FB, Giovannucci EL, Stampfer MJ, Willett WC, Fuchs CS, Bao Y. Associations between nut consumption and inflammatory biomarkers. Am J Clin Nutr. 2016 Sep;104(3):722-8. doi: 10.3945/ajcn.116.134205. Epub 2016 Jul 27. PubMed PMID: 27465378; PubMed Central PMCID: PMC4997300.
Harris WS, Mozaffarian D, Rimm E, Kris-Etherton P, Rudel LL, Appel LJ, Engler MM, Engler MB, Sacks F. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation. 2009 Feb 17;119(6):902-7. doi: 10.1161/CIRCULATIONAHA.108.191627. Epub 2009 Jan 26. PubMed PMID: 19171857.
Neuhouser ML, Schwarz Y, Wang C, Breymeyer K, Coronado G, Wang CY, Noar K, Song X, Lampe JW. A low-glycemic load diet reduces serum C-reactive protein and modestly increases adiponectin in overweight and obese adults. J Nutr. 2012 Feb;142(2):369-74. doi: 10.3945/jn.111.149807. Epub 2011 Dec 21. PubMed PMID: 22190020; PubMed Central PMCID: PMC3260063.
Bulló M, Casas-Agustench P, Amigó-Correig P, Aranceta J, Salas-Salvadó J. Inflammation, obesity and comorbidities: the role of diet. Public Health Nutr. 2007 Oct;10(10A):1164-72. Review. PubMed PMID: 17903326.
Jiang R, Jacobs DR Jr, Mayer-Davis E, Szklo M, Herrington D, Jenny NS, Kronmal R, Barr RG. Nut and seed consumption and inflammatory markers in the multi-ethnic study of atherosclerosis. Am J Epidemiol. 2006 Feb 1;163(3):222-31. Epub 2005 Dec 15. PubMed PMID: 16357111.
Nettleton JA, Steffen LM, Mayer-Davis EJ, Jenny NS, Jiang R, Herrington DM, Jacobs DR Jr. Dietary patterns are associated with biochemical markers of inflammation and endothelial activation in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr. 2006 Jun;83(6):1369-79. PubMed PMID: 16762949; PubMed Central PMCID: PMC2933059.
Song Y, Ridker PM, Manson JE, Cook NR, Buring JE, Liu S. Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care. 2005 Jun;28(6):1438-44. PubMed PMID: 15920065.
Alper CM, Mattes RD. Peanut consumption improves indices of cardiovascular disease risk in healthy adults. J Am Coll Nutr. 2003 Apr;22(2):133-41. PubMed PMID: 12672709.