Reproductive Health

Year Published: 2022

Journal

Research Square (Preprint)

Authors

Oluchi Nnenna ( à nwankudu.nnenna@mouau.edu.ng ) Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria Chukwuka Nwocha Uchendu University of Nigeria, Nsukka, Enugu State, Nigeria Reginald Ikechukwu Obidike University of Nigeria, Nsukka, Enugu State, Nigeria

Methods

NOTE: Preprint article. Peanut is a legume and contains L-3, 4-Phenyl Alanine which is a precursor for Dopamine. Dopamine is a prolactin inhibitor. A slight increase in prolactin leads to infertility. Objective: To investigate the effect of peanut extract on the reproductive performance of males

Key Findings

Methods: Thirty two adult albino rats comprising of 8 males and 24 females were used. The 8 males were divided into two groups (A and B) of 4 rats each. Group A (control) was given 2ml/kg of distilled water (DW), B was given 800mg/kg of Peanut Aqueous Extract (PAE) for 30 days. At day 21, 3 females were introduced to each male for impregnation. At day 31, the males were sacrificed. Blood was collected for hematology and serology. The females carried their pregnancy to term. Result: PAE treated male rats had significant (P ≤ 0.05) increase in testosterone, FSH and LH secretions. There was significant (P ≤ 0.05) increase in sperm concentration in PAE treated males than in control. Fertility indices showed that PAE treated male rats’ had 75% impregnation success while DW treated males had 42%. The results confirmed PAE as an aphrodisiac for male and for the treatment of hyperprolactinemia-induced-infertility and early stages of Parkinson’s disease.