Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis

Year Published: 2018


Lancet Public Health


Seidelmann SB, Claggett B, Cheng S, Henglin M, Shah A, Steffen LM, Folsom AR, Rimm EB, Willett WC, Solomon SD


Authors examined the relationship between carbohydrate intake and mortality, particularly in the context of low-carbohydrate diets. Data was taken from 14,428 adults in the Atherosclerosis Risk in Communitites (ARIC) study conducted between 1987-1989. They also assessed whether substituting animal or plant sources of fat and protein for carbohydrate affected mortality

Key Findings

Key Findings: Results showed that both low carbohydrate consumption and high carbohydrate consumption were associated with increased mortality. However, authors found that when carbohydrates were exchanged for plant-based fats and proteins including nuts and peanut butter, mortality significatly decreased. Mortality increased when carbohydrates were exchanged for animal-derived fats or proteins.