Mixture of Peanut Skin Extract and Fish Oil Improves Memory in Mice via Modulation of Anti-Oxidative Stress and Regulation of BDNF/ERK/CREB Signaling Pathways

Year Published: 2016

Journal

Nutrients

Authors

Xiang L, Cao XL, Xing TY, Mori D, Tang RQ, Li J, Gao LJ, Qi JH

Methods

Long term use of fish oil can increase the risk of Alzheimer's disease in humans. The authors of this paper sought to use peanut skin extract to lessen the adverse effects of fish oil in decreasing cognition. Mice were used for the study

Key Findings

Key Findings: Authors found that when fish oil was combined with peanut skin extract, this significantly increased cognition and memory in mice. They were able to identify that it worked because this mixture reduced oxidative stress. The application of peanut skin extract with fish oil may reduce its harmful effects and increase cognition to protect against Alzheimer's.