Mixture of Peanut Skin Extract and Fish Oil Improves Memory in Mice via Modulation of Anti-Oxidative Stress and Regulation of BDNF/ERK/CREB Signaling Pathways
Brain, Composition
Year Published: 2016
Journal
Nutrients
Authors
Xiang L, Cao XL, Xing TY, Mori D, Tang RQ, Li J, Gao LJ, Qi JH
Methods
Long term use of fish oil can increase the risk of Alzheimer's disease in humans. The authors of this paper sought to use peanut skin extract to lessen the adverse effects of fish oil in decreasing cognition. Mice were used for the study
Key Findings
Key Findings: Authors found that when fish oil was combined with peanut skin extract, this significantly increased cognition and memory in mice. They were able to identify that it worked because this mixture reduced oxidative stress. The application of peanut skin extract with fish oil may reduce its harmful effects and increase cognition to protect against Alzheimer's.