Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo

Year Published: 2019

Journal

Antioxidants (Basel)

Authors

Chen HY, Lin PH, Shih YH, Wang KL, Hong YH, Shieh TM, Huang TC, Hsia SM

Methods

In this study, authors injected uterine fibroid cells into mouse models and treated them with resveratrol, a potent polyphenol found in peanuts. Human fibroid cells were also treated in vitro.

Key Findings

Key Findings: Resveratrol significantly suppressed tumor cell growth and decreased cell proliferation. Authors conclude that resveratrol could potentially be used as an anti-fibrotic therapy for uterine fibroids.