Neither linoleic acid nor arachidonic acid promote white adipose tissue in Fads2-/- mice fed low fat diets

Year Published: 2017


Prostaglandins Leukot Essent Fatty Acids


Suitor K, Payne GW, Sarr O, Abdelmagid S, Nakamura MT, Ma DW, Mutch DM


In this mouse study, authors investigated the roles of linoleic acid and arachidonic acid in promoting inflammation in mice. The study utilized mice that could not convert linoleic acid to arachidonic acid. Linoleic acid is the main omega-6 fat in peanuts. Linoleic acid is normally converted to arachidonic acid endogenously.

Key Findings

Key Findings: Neither linoleic acid nor arachidonic acid promoted inflammation in mice. The authors concluded that the dogma surrounding omega-6 and its potential to cause inflammation needs to be considered.