Neuroprotective Effects of Proanthocyanidins, Natural Flavonoids Derived From Plants, on Rotenone-Induced Oxidative Stress and Apoptotic Cell Death in Human Neuroblastoma SH-SY5Y Cells
Brain, Overview
Year Published: 2018
Journal
Front Neurosci
Authors
Ma J, Gao SS, Yang HJ, Wang M, Cheng BF, Feng ZW, Wang L
Methods
Using a rat model to understand mechanisms, researchers investigated the effects of proanthocyanidin administration on outcomes associated with Parkinson's disease. Proanthocyanidins are flavonoid compounds that are found in peanuts.
Key Findings
Key Findings: Results showed that proanthocyanidins protected against cellular death and cell damage from reactive oxygen species. Authors concluded that proanthocyanidins may be effective in treating Parkinson's Disease.
