p-Coumaric acid activates the GABA-A receptor in vitro and is orally anxiolytic in vivo
Brain, Composition
Year Published: 2014
Journal
Phytother Res
Authors
Scheepens A, Bisson JF, Skinner M
Methods
In this study, authors investigated the effect of p-coumaric acid on GABA. P-coumaric acid is a prominent antioxidant in peanuts. GABA is a neurotransmitter that regualted mood, stress, and anxiety
Key Findings
Key Findings: Results showed that p-coumaric acid was able to target the neurotransmitter GABA, and subsequently decrease anxiety and stress. Authors noted that p-coumaric acid had similar effects for reducing stress as one of the leading anxiety-reducing drugs, Diazepam.
