Recent advances on the effect of nut consumption on cognitive improvement
Brain Health, Cognition
Year Published: 2023
Weijie Wu, Ben Niu, Liang Peng, Qi Chen, Huizhi Chen, Hangjun Chen, Wei Xia, Long Jin, Jesus Simal-Gandara, Haiyan Gao
Cognitive disorders, including dementia, Parkinson’s and Alzheimer’s disease, pose significant public health issues. Preventing/delaying their onset is essential as effec- tive medical treatments are unavailable. Nuts contain bioactive compounds, including fatty acids, macronutrients such as proteins and dietary fibers, micronutrients, and polyphenols; these act synergistically preventing age-related diseases. Epidemiolog- ical investigations have established that high nut consumption reduces cognitive impairment risk, suggesting it is useful for cognitively impaired individuals; however, clinical data on the effects of nut consumption on cognitive function are lacking. This review summarized nut consumption effects on oxidative stress, inflammatory response, and gut microbiota.
Key Findings: Nuts reduce oxidative stress; their active substances, including glansreginin A, proanthocyanidins, quercetin, and nut oil, have signifi- cant anti-inflammatory effects. Furthermore, they comprise complex mixtures, which synergistically induce beneficial changes in the intestinal microbial community.